Vacation Message ?

I have this situation… there is an info@domain.com adres and that mail is forwarded to 2 users. User1@domain.com and User2@domain.com

For user2@domain.com there is a vacation message.

When i mail to info@domain.com the mail will be forwarded to the users… but from user2@domain.com i get the holliday message…

Is it possible NOT te reply on my mail when the mail to info@domain.com is forwarded to the user ?
Mailing the user directly works fine. I get the holliday message as aspected.

I hope i post it right here…

Hoping for a solution

best regards,

John