Exim(13) Permission Denied Error

Hello, email is not being processed on my server and started getting this error

Quote:

2012-06-26 10:11:49 email.server.com <root@server.server.com> R=virtual_user T=virtual_localdelivery defer (13): Permission denied: failed to open tmp/1340727109.H44617P1194.server.server.com (10 tries)


Any help would be appreciated. Thanks